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This is a classification of tumours and tumour-like lesions of the
liver. It is based primarily on the microscopic characteristics of
the tumours, and is therefore concerned with morphologically
identi- fiable cell types and histological patterns. The
haematoxylin- and eosin-stained section remains the mainstay of
morphological diag- nosis, but special histochemical stains are
often helpful and have been referred to in the explanatory notes.
Readers interested in specific special stains mentioned in the text
should consult Labora- tory Methods in Histotechnology of the Armed
Forces Institute of *Pathology, Washington, D. c., USA. 1 The
results of immunohisto- chemical methods for identifying various
tumour "markers" have also been noted whenever indicated. The
present classification incorporates all the previously classi- fied
tumours, but also includes several new lesions, viz. biliary papil-
lomatosis, the fibrolamellar variant of hepatocellular carcinoma
and epithelioid haemangioendothelioma. Several subtypes of hepato-
blastoma are mentioned. A serous type of bile duct cystadenoma is
described. The section on tumour-like lesions has been expanded to
include focal fatty change and inflammatory pseudotumour. The
section on adenomatous hyperplasia, including macroregenerative
nodules, has been amplified. The number of photomicrographs has
been increased from the original 56 to 150. Unlike the first
edition, the photomicrographs in the second edition are mostly
black and white. All are new and were taken of representative cases
on file at the Armed Forces Institute of Pathology.
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